Microdosing Magic Mushrooms: Positive Effects You Can Expect

Microdosing magic mushrooms, or consuming sub-perceptual doses of psilocybin, has garnered significant attention for its potential health benefits. Unlike full doses that lead to intense psychedelic experiences, microdosing involves taking about 1/10th to 1/20th of a recreational dose, enough to produce subtle effects without hallucinations. This practice has surged in popularity, particularly among individuals seeking mental health benefits, enhanced creativity, and improved cognitive function. This article explores the myriad ways microdosing magic mushrooms can be beneficial, supported by scientific studies and anecdotal evidence.

Introduction to Microdosing

Microdosing involves regularly consuming very small amounts of a psychedelic substance, typically every few days. The concept, popularized by Dr. James Fadiman’s 2011 book, “The Psychedelic Explorer’s Guide,” suggests that these minuscule doses can improve mental and physical well-being without the intense effects associated with larger doses. This practice, while still somewhat controversial, is becoming increasingly mainstream as more people report positive experiences and research begins to validate these claims.

Historical Context

Psilocybin, the active compound in magic mushrooms, has been used for centuries in various cultures for religious and healing purposes. Indigenous tribes in Mesoamerica have used these mushrooms in their rituals, valuing their profound effects on consciousness and spirituality. In the mid-20th century, Western science began exploring psilocybin’s potential, leading to numerous studies on its therapeutic benefits. However, due to the stigmatization and legal restrictions that followed, research was halted for several decades, only to experience a resurgence in recent years as societal attitudes towards psychedelics shift.

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Enhancing Creativity and Productivity

Creativity Enhancement

One of the most celebrated benefits of microdosing magic mushrooms is its impact on creativity and productivity. Users report enhanced creative thinking, problem-solving abilities, and increased productivity. A study published in the journal “Psychopharmacology” found that low doses of psychedelics could enhance divergent thinking, a key component of creativity. This study aligns with anecdotal reports from individuals in creative fields who microdose to break through creative blocks and generate novel ideas.

Productivity and Focus

In addition to boosting creativity, microdosing is reported to improve focus and productivity. Professionals from various sectors, including technology and the arts, use microdosing to enhance their ability to concentrate on complex tasks, maintain prolonged periods of productivity, and stay motivated. A survey conducted by the Beckley Foundation indicated that microdosing could lead to a more structured and effective work routine, helping individuals achieve their professional goals more efficiently.

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Improving Mental Health

Reducing Anxiety and Depression

Microdosing has shown promise in alleviating symptoms of anxiety and depression. A 2019 study by Polito and Stevenson published in “PLOS ONE” found that individuals who microdosed reported lower levels of depression and stress. The mechanism behind this effect is believed to be related to psilocybin’s ability to increase neuroplasticity and promote the growth of new neural connections, as shown in a study by the Beckley Foundation. This ability to create new neural pathways can help “reset” the brain, leading to long-lasting changes in mood and outlook.

Enhancing Mood and Emotional Well-being

Regular microdosing has been linked to improved mood and emotional stability. Participants in various studies and self-reported surveys have noted a general uplift in their mood, reduced irritability, and a greater sense of well-being. These effects are believed to stem from psilocybin’s interaction with serotonin receptors in the brain, which play a critical role in regulating mood. The increase in serotonin activity can result in a more balanced and positive emotional state, contributing to overall mental health.

Boosting Cognitive Function

Cognitive Flexibility

Microdosing can also enhance cognitive function, including improved focus, concentration, and mental clarity. A study conducted by Prochazkova et al. and published in the “Journal of Psychopharmacology” in 2018 found that microdosing could improve cognitive flexibility, which is the brain’s ability to switch between thinking about different concepts or to think about multiple concepts simultaneously. This cognitive enhancement is particularly beneficial for tasks requiring sustained attention and creative problem-solving.

Memory and Learning

Furthermore, microdosing may positively affect memory and learning. Psilocybin has been shown to facilitate the growth of new neurons and strengthen synaptic connections, essential for memory formation and retention. This neurogenesis can lead to improved learning capabilities, making it easier to acquire and recall new information.

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Physical Health Benefits

Reducing Inflammation

Emerging research suggests that psilocybin may have anti-inflammatory properties. Chronic inflammation is linked to a range of health issues, including autoimmune diseases, cardiovascular disease, and neurodegenerative disorders. By potentially reducing inflammation, microdosing psilocybin could contribute to overall physical health and longevity. The anti-inflammatory effects of psilocybin could also help in managing chronic pain conditions, providing a natural alternative to traditional pain management strategies.

Enhancing Physical Performance

Some users report enhanced physical performance and endurance when microdosing. While scientific evidence in this area is still emerging, the anecdotal experiences suggest that microdosing can increase motivation and reduce fatigue, which can be beneficial for physical activities. Athletes and fitness enthusiasts have noted improvements in their training sessions, citing increased energy levels and faster recovery times.

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Promoting Neurogenesis and Neuroplasticity

Psilocybin has been shown to promote neurogenesis (the growth of new neurons) and neuroplasticity (the brain’s ability to reorganize itself by forming new neural connections). A 2016 study by Catlow et al. published in “Experimental Brain Research” demonstrated that psilocybin could stimulate neurogenesis in the hippocampus, an area of the brain crucial for learning and memory. This property is particularly promising for treating conditions like depression, PTSD, and Alzheimer’s disease, where neuroplasticity is often impaired.

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Enhancing Spiritual and Personal Growth

Microdosing can also facilitate spiritual and personal growth. Many users report a heightened sense of connection to themselves, others, and the universe. This sense of interconnectedness can foster greater empathy, compassion, and a deeper understanding of one’s purpose in life. These experiences, while subtle, can lead to profound personal transformations over time. Enhanced introspection and a deeper sense of meaning are often cited as significant benefits, contributing to an overall sense of fulfillment and happiness.

Supporting Addiction Recovery

Emerging evidence suggests that psilocybin could be beneficial in treating addiction. A study published in “The Journal of Psychopharmacology” in 2015 found that psilocybin-assisted therapy significantly improved abstinence rates in individuals with alcohol dependence. Microdosing, by promoting neuroplasticity and enhancing mood, may support individuals in breaking free from addictive behaviors and developing healthier habits. The potential of microdosing in addiction therapy could revolutionize current treatment approaches, offering a new pathway to recovery

Practical Considerations for Microdosing

Dosage and Frequency

Finding the right dosage is crucial for effective microdosing. The typical microdose ranges from 0.1 to 0.3 grams of dried magic mushrooms, taken every three to four days. It’s important to start with a lower dose and gradually adjust based on individual response. The goal is to find a dose that produces noticeable improvements in well-being without causing perceptual changes.

Safety and Preparation

Ensuring the quality and purity of the mushrooms is essential. It’s recommended to obtain them from a reliable source and to be mindful of potential interactions with other medications. Consulting with a healthcare provider before starting a microdosing regimen is advisable, especially for individuals with underlying health conditions. Proper preparation and storage are also important to maintain the mushrooms’ potency and safety.

Tracking and Adjusting

Keeping a journal to track the effects of microdosing can help in fine-tuning the dosage and frequency. Noting changes in mood, cognitive function, and overall well-being can provide valuable insights into how microdosing is impacting one’s life. This practice allows individuals to identify patterns and make informed adjustments to their regimen.

Personal Anecdotes and Case Studies

The growing body of anecdotal evidence highlights the diverse benefits of microdosing. Many individuals have shared their experiences of enhanced creativity, improved mental health, and personal growth. These personal stories, while subjective, provide a compelling narrative that complements scientific research. Case studies often reveal the profound impact microdosing can have on individual lives, offering hope and inspiration to others considering this practice.

Potential Challenges and Considerations

While microdosing has numerous potential benefits, it’s important to acknowledge the challenges and considerations. Individual responses to psilocybin can vary, and not everyone may experience the same positive effects. Additionally, the long-term effects of regular microdosing are still not fully understood, necessitating further research. There is also the risk of developing a psychological dependency on the practice, although this is generally considered low.

Future Directions and Research

The field of psychedelic research is rapidly evolving, with numerous ongoing studies exploring the therapeutic potential of microdosing. As scientific interest grows, more robust clinical trials are expected to provide deeper insights into the mechanisms and benefits of microdosing magic mushrooms. This research will be crucial in validating anecdotal reports and expanding our understanding of psilocybin’s effects on the human brain and body. Future studies may also explore the long-term effects of microdosing, providing a more comprehensive understanding of its safety and efficacy.

Broader Implications for Society

The potential benefits of microdosing magic mushrooms extend beyond individual health and well-being. If validated by further research, microdosing could have significant implications for public health, mental health care, and even productivity in the workplace. The integration of microdosing into mainstream health practices could lead to more innovative and effective approaches to treating a wide range of conditions.

Integrating Microdosing into Daily Life

For those considering microdosing, integrating this practice into daily life involves careful planning and mindful reflection. Establishing a routine, setting clear intentions, and monitoring progress are key steps to ensure a positive experience. Community support and sharing experiences with others can also provide valuable insights and encouragement.

Ethical and Environmental Considerations

As interest in microdosing grows, it’s important to consider the ethical and environmental impacts. Sustainable sourcing of magic mushrooms and promoting responsible use are essential to protect natural ecosystems and ensure the well-being of all individuals involved. Advocating for ethical practices and environmental stewardship can help create a more sustainable and equitable approach to psychedelic use.

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Conclusion

Microdosing magic mushrooms offers a promising avenue for enhancing mental health, creativity, cognitive function, and overall well-being. Supported by both scientific research and anecdotal evidence, this practice holds the potential to revolutionize our approach to mental and physical health. As research continues to unfold, microdosing may become a widely accepted and valued tool for personal growth and healing.

By integrating microdosing into a holistic approach to well-being, individuals can tap into the profound benefits of psilocybin, fostering a deeper connection to themselves and the world around them. As we continue to explore the potential of this ancient medicine, microdosing stands as a beacon of hope in the quest for mental and emotional wellness.

The journey of exploring microdosing is both personal and transformative. As more people share their stories and as science continues to uncover the mysteries of psilocybin, we move closer to a future where microdosing is recognized not only for its therapeutic potential but also for its capacity to enhance the human experience in profound and meaningful ways.

References

  1. Polito, V., & Stevenson, R. J. (2019). A systematic study of microdosing psychedelics. PLOS ONE, 14(2), e0211023.
  2. Prochazkova, L., Lippelt, D. P., Colzato, L. S., Kuchar, M., & Hommel, B. (2018). Exploring the effect of microdosing psychedelics on creativity in an open-label natural setting. Psychopharmacology, 235(12), 3401-3413.
  3. Catlow, B. J., Song, S., Paredes, D. A., Kirstein, C. L., & Sanchez-Ramos, J. (2016). Effects of psilocybin on hippocampal neurogenesis and extinction of trace fear conditioning. Experimental Brain Research, 235(3), 2485-2493.
  4. Johnson, M. W., Garcia-Romeu, A., & Griffiths, R. R. (2017). Long-term follow-up of psilocybin-facilitated smoking cessation. The American Journal of Drug and Alcohol Abuse, 43(1), 55-60.
  5. Bogenschutz, M. P., Forcehimes, A. A., Pommy, J. A., Wilcox, C. E., Barbosa, P. C., & Strassman, R. J. (2015). Psilocybin-assisted treatment for alcohol dependence: A proof-of-concept study. Journal of Psychopharmacology, 29(3), 289-299. 

Golden Teacher Magic Mushrooms: Everything You Need to Know

Introduction

Welcome to the most comprehensive and insightful guide on Golden Teacher Magic Mushrooms. If you’re curious about these remarkable fungi, you’ve come to the right place. In this article, we will delve deep into the world of Golden Teacher Magic Mushrooms, exploring their history, identification, cultivation, effects, potential benefits, and much more. By the end, you’ll have a wealth of knowledge to better understand and appreciate these mystical mushrooms.

History and Origins

The history of Golden Teacher Magic Mushrooms is steeped in mysticism and tradition. Indigenous cultures across the globe have used them for centuries, with their usage dating back to ancient times. The name “Golden Teacher” reflects their reputation for imparting valuable insights and life-changing experiences.

These mushrooms have played a significant role in various indigenous rituals and ceremonies. They have been revered as tools for connecting with the spiritual world and gaining profound insights into life, nature, and the cosmos. Some cultures even considered them a gift from the gods, a conduit to higher realms of consciousness.

Identifying Golden Teacher Magic Mushrooms

Before embarking on a quest with Golden Teacher Magic Mushrooms, it’s vital to be able to identify them accurately. Accurate identification ensures a safe and rewarding experience. Here are some key features to look for when identifying Golden Teacher Magic Mushrooms:

  1. Cap Color: Golden Teacher Magic Mushrooms have caps that range from golden to light brown, often with a distinctive bump or nipple-like protrusion at the center. The cap typically measures between 2 to 5 centimeters in diameter.
  2. Stem Color: The stem of these mushrooms is pale white with a fibrous texture. It’s usually cylindrical and can grow up to 10-15 centimeters in length.
  3. Gills: The gills of Golden Teacher Magic Mushrooms are dark purplish-brown when young, becoming lighter with age. They are densely spaced and run from the stem to the edge of the cap.
  4. Spore Print Color: To further confirm the identification, you can take a spore print. The spore print of Golden Teacher Magic Mushrooms is typically dark purple-brown.

These distinctive characteristics will help you distinguish Golden Teacher Magic Mushrooms from other mushroom species, ensuring a safe and rewarding experience.

Cultivation and Growing Process

If you’re curious about cultivating your own Golden Teacher Magic Mushrooms, you’re in for an exciting journey. Cultivating these mushrooms can be a rewarding and educational experience. To embark on this endeavor, you’ll need some essential components, including spore syringes, a suitable substrate, and a controlled environment.

The cultivation process involves several steps, including sterilizing the substrate, inoculating it with spores, maintaining proper humidity and temperature levels, and allowing the mushrooms to grow and mature. Detailed step-by-step guides and resources are available to assist you in achieving a successful harvest.

The cultivation of Golden Teacher Magic Mushrooms not only provides a source of these remarkable fungi but also offers a deeper understanding of their life cycle and growth patterns. It’s important to note that cultivating magic mushrooms may be subject to legal restrictions in some regions, so it’s essential to research and adhere to local laws and regulations.

Effects and Experiences

Consuming Golden Teacher Magic Mushrooms can lead to a wide range of experiences, each unique to the individual and dosage. These mushrooms contain psychoactive compounds, most notably psilocybin and psilocin, which are responsible for their effects on the mind and consciousness.

Some common effects of Golden Teacher Magic Mushrooms include:

  1. Euphoria: Many users report feelings of euphoria and intense happiness. The sense of joy and interconnectedness with the world can be profound.
  2. Introspection: These mushrooms often lead to deep introspective experiences, allowing individuals to explore their thoughts, emotions, and life from a different perspective.
  3. Vivid Hallucinations: At higher doses, Golden Teacher Magic Mushrooms can induce vivid hallucinations, including visual, auditory, and even sensory distortions.
  4. Spiritual Insights: Some users describe a profound sense of spirituality and a connection to the universe while under the influence of these mushrooms.

It is crucial, however, to approach these mushrooms with care and in a controlled setting to ensure a positive and safe experience. The effects can vary depending on factors such as dosage, individual sensitivity, and the surrounding environment. Responsible and mindful use is essential to maximize the potential benefits and minimize risks.

Potential Benefits

Recent research has shed light on the potential therapeutic benefits of Golden Teacher Magic Mushrooms. While further studies are needed, these mushrooms have shown promise in addressing various mental health issues, including depression, anxiety, and post-traumatic stress disorder (PTSD).

  1. Depression: Some studies suggest that psilocybin, the primary psychoactive compound in these mushrooms, may have antidepressant properties. It is believed to work by promoting neural plasticity and facilitating new perspectives on life and personal challenges.
  2. Anxiety: Golden Teacher Magic Mushrooms may help individuals with anxiety disorders by inducing a sense of calm, reducing the fear response, and promoting relaxation.
  3. PTSD: Research indicates that psychedelic experiences, guided by trained therapists, may assist in processing traumatic memories and reducing the symptoms of PTSD.

While promising, it’s essential to consult with a medical professional before considering Golden Teacher Magic Mushrooms as a treatment option. Psychedelic therapy should always be conducted under the guidance of trained professionals in a controlled and supportive environment.

FAQs

Q: Are Golden Teacher Magic Mushrooms legal?

A: The legal status of Golden Teacher Magic Mushrooms varies from one region to another. It’s imperative to research and adhere to local laws and regulations before acquiring or using them. In some places, these mushrooms are classified as illegal substances, while in others, they may be decriminalized or available for medical use.

Q: How do I consume Golden Teacher Magic Mushrooms?

A: These mushrooms can be consumed in various forms, including fresh, dried, or brewed into a tea. The method of consumption can affect the onset and duration of the effects. It’s advisable to start with a low dose and gradually increase it to find your comfort level while avoiding overwhelming effects.

Q: Are there any potential risks?

A: Yes, like any substance, Golden Teacher Magic Mushrooms come with potential risks. Users may experience adverse effects such as nausea, anxiety, or confusion, especially at higher doses. Responsible use in a safe environment is crucial to minimize these risks.

Q: Can I microdose with Golden Teacher Magic Mushrooms?

A: Microdosing, which involves taking sub-perceptual doses of psychedelics, has gained popularity for its potential cognitive and mood-enhancing benefits. However, it’s essential to follow a precise dosing regimen and monitor how it affects your mental and emotional well-being. Microdosing should also be approached with caution and in consultation with a healthcare professional.

Q: Are there any interactions with medications?

A: Golden Teacher Magic Mushrooms may interact with certain medications. If you are taking any prescription drugs, consult a healthcare professional before using them. Some interactions can be potentially harmful, so it’s essential to ensure your safety.

Q: How can I store Golden Teacher Magic Mushrooms?

A: To maintain their potency, store these mushrooms in an airtight container in a cool, dark place. Keeping them dry and protected from light is essential to preserve their psychoactive compounds.

Q: Can I buy Golden Teacher Magic Mushrooms in Canada?

A: Absolutely! The highest quality Golden Teacher magic mushrooms available can be purchased at our store! Buy Golden Teacher Shrooms here!

Conclusion

Golden Teacher Magic Mushrooms offer a profound and enlightening journey into the realms of consciousness. This comprehensive guide has equipped you with valuable insights into their history, identification, cultivation, effects, and potential benefits. As you explore this captivating world, always approach it with respect, responsibility, and an unwavering commitment to safety.

Intriguing and enigmatic, Golden Teacher Magic Mushrooms continue to inspire curiosity and research, offering a bridge between science, spirituality, and the exploration of the human mind. Whether used recreationally or as a tool for personal growth and healing, these mushrooms remain a subject of fascination and wonder for those who seek to unlock the secrets of their transformative potential.

The Healing Power of Psilocybin: Stories of Transformation

The Healing Power of Psilocybin: Stories of Transformation

Introduction

In recent years, a remarkable resurgence in psychedelic research has shed light on the profound healing potential of substances like psilocybin, found in certain species of mushrooms. This resurgence has brought to the forefront incredible stories of personal transformation and therapeutic breakthroughs. In this article, we will delve into the world of psilocybin, exploring its history, the science behind its healing power, personal stories of transformation, legal implications, its impact on mental health, responsible use, comparisons with traditional treatments, the role of guides and therapists, controversies, and the exciting future possibilities.

What is Psilocybin?

Understanding Psilocybin Mushrooms Imagine a lush forest where vibrant, otherworldly mushrooms with colorful caps emerge from the damp earth. These mushrooms, known as psilocybin mushrooms or “magic mushrooms,” have been revered for centuries by indigenous cultures worldwide. They have been used in rituals and ceremonies to connect with the spirit world, gain insights, and facilitate healing.

Historical Use Centuries ago, in the heart of the Amazon rainforest, indigenous tribes gathered around a ceremonial fire, consuming psilocybin-containing mushrooms as part of a sacred ritual. Their intention was to communicate with ancestors and heal the sick. This historical use of psilocybin mushrooms spans continents, offering a rich tapestry of tradition and spirituality.

The Science Behind Psilocybin’s Healing Power

Psychedelic Research Resurgence In the mid-20th century, the exploration of psychedelics, including psilocybin, was stifled by stringent regulations. However, recent years have witnessed a revival of scientific interest. Imagine researchers conducting clinical trials where participants, guided by trained therapists, embark on inner journeys using psilocybin. These studies are uncovering profound insights into the human mind and its potential for healing and transformation.

How Psilocybin Works in the Brain Picture the human brain as a vast network of interconnected neurons. When psilocybin enters the bloodstream and crosses the blood-brain barrier, it binds to serotonin receptors, specifically the 5-HT2A receptor. This binding leads to alterations in perception, mood, and cognition. The brain’s default mode network, responsible for our sense of self and ego, undergoes temporary dissolution. This can be likened to a refreshing reset button for the mind, offering a unique opportunity for introspection and healing.

Stories of Transformation

Personal Accounts of Healing Meet Sarah, a 35-year-old woman from Chatham, ON who struggled with treatment-resistant depression for years. Traditional therapies and medications provided little relief. However, after learning she can buy magic mushrooms online at Shroom Bros, Sarah experienced a profound shift in her perspective. She describes it as if she had been wearing dark glasses her entire life, and suddenly, the world appeared in vibrant color. Sarah’s story is just one of many, illustrating the potential of psilocybin to offer hope and healing where other approaches have fallen short.

Therapeutic Applications Imagine a therapeutic setting where a trained therapist guides individuals through a carefully designed psilocybin session. These sessions are not about escape but rather a deep dive into one’s psyche. They are a safe space for confronting and processing unresolved emotions, traumas, and anxieties. Clinical trials have demonstrated remarkable results, with individuals reporting reduced symptoms of depression, anxiety, and PTSD after just a few sessions. Psilocybin’s capacity to reveal the underlying causes of mental suffering is at the heart of its therapeutic promise.

The Legal Landscape

Decriminalization and Medical Use Picture a city where local authorities have decided to decriminalize the possession and use of psilocybin for personal use. This change reflects a growing recognition of the substance’s potential benefits. In other regions, medical professionals are legally permitted to administer psilocybin in controlled therapeutic settings, offering a lifeline to those who have exhausted traditional treatment options.

Legal Status Worldwide The legal status of psilocybin varies worldwide. Some countries strictly regulate its possession and use, while others have adopted more progressive approaches. It is essential for individuals to be aware of and respect the laws and regulations in their respective regions.

 

Psilocybin and Mental Health

Depression and Anxiety Imagine a future where individuals with severe depression or debilitating anxiety find relief through psilocybin therapy. Clinical trials have shown that a single session can lead to significant reductions in depressive symptoms that can last for months. It’s akin to lifting a heavy fog that has obscured one’s emotional well-being for years.

PTSD and Trauma Visualize a war veteran who has struggled for years with debilitating PTSD. Through guided psilocybin therapy sessions, they can finally confront and process the traumatic experiences that have haunted them. The therapeutic potential of psilocybin in addressing PTSD is nothing short of transformative.

Safety and Responsible Use

Setting and Preparation Envision a comfortable room bathed in soft, warm light. A trained therapist sits nearby, offering emotional support. This is the setting for a psilocybin therapy session, carefully designed to ensure comfort and safety. Prior to the experience, participants engage in preparation sessions, setting intentions and addressing any fears or concerns.

Guidance and Integration Consider the guidance provided by experienced therapists during a psilocybin session as akin to a trusted hand that guides you through unfamiliar terrain. After the session, integration therapy helps individuals make sense of their experiences and apply the insights gained to their daily lives. It’s a process of transformation that extends beyond the psychedelic journey itself.

Psilocybin vs. Traditional Treatments

Comparing Efficacy Imagine comparing the effectiveness of traditional antidepressant medications, which often provide partial relief, to the profound shifts experienced by individuals through psilocybin therapy. While traditional treatments have their place, psilocybin offers a different paradigm of healing—one that addresses the root causes of mental suffering.

Side Effects and Risks While psilocybin is generally considered safe when used responsibly, it is not without potential risks. Nausea, anxiety during the experience, and, in rare cases, enduring psychological distress can occur. However, when administered in a controlled and supportive setting, the risks are significantly mitigated.

The Role of Guides and Therapists

The Importance of Professional Guidance Imagine navigating the uncharted waters of a psychedelic journey without an experienced guide. Trained therapists provide invaluable support, ensuring that participants feel safe and supported throughout the experience. Their expertise can mean the difference between a transformative journey and a potentially challenging one.

Integration Therapy Integration therapy is the bridge that connects the insights gained during a psilocybin session with one’s everyday life. It’s like translating a beautiful but cryptic dream into meaningful actions and changes. Therapists assist individuals in processing their experiences, helping them make lasting positive changes.

Challenges and Controversies

Ethical Concerns As psilocybin gains popularity, ethical concerns have emerged. Imagine a scenario where an individual, eager to experience psilocybin’s effects, fails to fully understand its potential risks and benefits. Informed consent and responsible use are ethical imperatives in the world of psychedelics.

Misuse and Abuse While responsible use of psilocybin for therapeutic purposes is showing great promise, recreational use carries inherent risks. Visualize a group of friends in a recreational setting, consuming psilocybin without guidance or intention. Education and responsible consumption practices are essential to prevent misuse and potential harm.

Future Possibilities

Ongoing Research Picture a future where psilocybin therapy is not limited to mental health but extends to treating addiction, end-of-life distress, and neurodegenerative disorders like Alzheimer’s disease. Ongoing research is uncovering the vast potential of this remarkable substance, paving the way for innovative therapeutic applications.

Conclusion

In conclusion, the healing power of psilocybin is an exciting frontier in modern medicine and psychology. With its potential to transform lives and alleviate suffering, psilocybin is gaining recognition as a valuable tool in mental health treatment. However, it is essential to approach its use with caution, respecting legal regulations and seeking guidance from qualified professionals. As we continue to explore its possibilities, the future of psilocybin therapy holds promise for individuals seeking healing and transformation.

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Frequently Asked Questions (FAQs)

  1. Is psilocybin legal everywhere?
    • The legal status of psilocybin varies by country and region. It is essential to research and understand the laws in your area before considering its use.
  2. How does psilocybin therapy compare to traditional psychiatric treatments?
    • Psilocybin therapy offers a unique approach that may be effective for some individuals who have not responded well to traditional treatments. It involves guided sessions in which individuals experience profound insights.
  3. Are there any potential side effects of using psilocybin?
    • While psilocybin is generally safe, it can lead to short-term side effects such as nausea and anxiety during the experience. In rare cases, enduring psychological distress may occur.
  4. What role do therapists play in psilocybin-assisted therapy?
    • Therapists and guides provide emotional support, ensure a safe environment, and help individuals navigate their psychedelic experiences. They also assist in post-session integration therapy.
  5. What does the future of psilocybin research look like?
    • The future of psilocybin research is promising, with ongoing studies exploring its potential in various areas, including addiction treatment, end-of-life care, and neurodegenerative disorders. As our understanding grows, so does the potential for innovative therapeutic applications.

How do Magic Mushrooms Affect the Brain

With regard to hallucinogens like psilocybin—an ingredient of so-called “magic mushrooms” (e.g., Psilocybe cubensis)—it may be high time to reconsider long-standing hypotheses related to their actions in the human brain.

Although psilocin (the active metabolite of psilocybin)and other classical hallucinogens like lysergic acid diethylamide (LSD) have complex pharmacology with high affinities for multiple neurotransmitter receptors, it has long been appreciated that their psychedelic actions correlate best with 5-HT2A–serotonin receptor agonism. Indeed, in 5-HT2A knockout mice, classical hallucinogens are devoid of activity. Importantly, the psychedelic actions of psilocybin in humans are abolished by pretreatment with relatively selective 5-HT2A antagonists. Taken together, these findings support the hypothesis that psilocybin and other classical hallucinogens exert their psychedelic actions in humans via activating 5-HT2A serotonin receptors.

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Psilocybin diminishes brain activity and connectivity. (A) Psilocybin, which is inactive, is metabolized to the active ingredient psilocin. Psilocin then activates many neurotransmitter receptors (B) to modulate activity on excitatory pyramidal and inhibitory GABA-ergic neurons (C). (B) Affinity values for psilocin are expressed as –log in nanomoles (pKi) and are from the National Institute of Mental Health Psychoactive Drug Screening Programs Ki Database. (C) Psilocin interacts with various receptors on large excitatory pyramidal neurons and smaller inhibitory neurons. Psilocin may interact with excitatory (orange) or inhibitory (red) receptors to augment or inhibit neurotransmission. Psilocin’s net effect is a decrease in neuronal activity and connectivity as measured by fMRI.

Although there is consensus regarding the pharmacological actions of classical hallucinogens, the neuronal mechanisms responsible for the psychedelic actions of hallucinogens remain controversial. Thus, some investigators have observed that LSD-like hallucinogens can enhance pyramidal neuron activity by activating 5-HT2A serotonin receptor signaling. These findings that hallucinogens activate glutamatergic neurotransmission are consistent with many other studies demonstrating that 5-HT2A receptors were enriched on Layer V glutamatergic neurons although we and others have noted that 5-HT2A receptors are also found on GABA-ergic interneurons. Indeed, 5-HT2A agonists can also augment inhibitory neuronal activity. Taken together, these previous findings have implied that the actions of hallucinogens such as psilocybin might be due to a mixture of actions on both excitatory (e.g., pyramidal) and inhibitory (e.g., GABA-ergic interneuronal) neuronal circuits. Conceivably, then, hallucinogens like psilocybin could induce their psychedelic effects via augmenting either excitatory or inhibitory neuronal activity in humans. Unfortunately, because of medical, legal, human use, and societal concerns, well-controlled studies of hallucinogen actions in humans have languished since the early 1960s.

In PNAS, Carhart-Harris et al. successfully execute an important study that begins to fill in our gaps regarding hallucinogen actions in humans. Surprisingly, they demonstrate that psilocybin decreases surrogate markers for neuronal activity [cerebral blood flow and blood oxygen level-dependent (BOLD) signals] in key brain regions implicated in psychedelic drug actions. They also report that psilocybin appears to decrease brain “connectivity” as measured by pharmaco-physiological interaction.

To perform these studies, Carhart-Harris et al. recruit 15 experienced hallucinogen users for arterial spin labeling (ASL) perfusion and BOLD fMRI studies. The individuals were scanned before and after receiving i.v. doses of placebo or psilocybin (2 mg). Individuals were also rated for the subjective effects of psilocybin or placebo. Not surprisingly, psilocybin exerted a robust psychedelic effect with individuals reporting alterations in consciousness, time perception, and visual perceptions within minutes of psilocybin administration.

Coincident with these profound perceptual alterations, decreases in cerebral blood flow were observed in key brain regions long implicated in psychedelic drug actions—the anterior and posterior cingulate cortices and thalamus. Intriguingly, the intensity of the psychedelic experience significantly correlated with decrements in blood flow in the thalamus and anterior cingulate cortex. Carhart-Harris et al. also report what they refer to as decreases in “functional connectivity” between the ventral medial

Psilocybin appears to decrease brain “connectivity” as measured by pharmaco-physiological interaction.

prefrontal cortex and other regions that they interpret to indicate overall diminished connectivity.

Overall, these findings are consistent with the hypothesis that psilocybin diminishes activity in key brain regions and networks implicated in hallucinogen actions. These provocative findings are important because they challenge many long-held models regarding hallucinogen actions that have focused mainly on their ability to enhance excitatory neurotransmission and overall brain activity.

The findings of Carhart-Harris et al. are also important because they provide nice proof that, provided appropriate safeguards are in place, psychedelic drug actions can once again be rigorously deconstructed in normal human volunteers. Psychedelic drugs are unique in their abilities to profoundly alter human awareness and perception, and these studies provide important hints regarding the neuronal substrates of human consciousness.

HOW DO MAGIC MUSHROOMS AFFECT THE BRAIN?

This study is based on brain images taken from nine participants who were either injected with psilocybin or a placebo. The scientists used those images to create a “whole-brain connectome” which provides a picture of all the physical neurons in the brain, as well as the activity of the neurotransmitters that are being shuttled back and forth.

During your average day in the human brain, neurons are constantly firing and neurotransmitters are traveling well-trodden paths through the brain, somewhat like cars on a freeway. On magic mushrooms, those networks are “destabilized”, Kringlebach explains.

Previous research has shown that new networks appear in tandem. It’s as if those cars on the freeway were given free rein to stray from the highway and take back roads towards new destinations.

Scientists are beginning to understand how this works. For instance, psilocybin (as well as psychedelics like DMT) mimic serotonin, a neurotransmitter related to feelings of happiness or love. Kringelbach suggests that these mushrooms do more than simply affect serotonin flow in the brain.

“We wanted to investigate the role of neurotransmission in dynamically changing the activity in whole-brain networks — and how this changes neurotransmitter release in return,” he explains.

The models showed that the brain is able to tap into new networks by coupling the effects of neuron activity and the release of neurotransmitters, like serotonin. The release of neurotransmitters and the firing of neurons work together – and when you have one without the other, the whole system falls apart.

When the scientists adjusted their model to have these processes work independently, they found that they weren’t able to recreate the same “destabilization” of networks that you would usually see when someone is on magic mushrooms. The same breakdown in their pattern happened when they replaced the typical serotonin receptors utilized by magic mushrooms (5-HT2A receptors) with other types of serotonin receptors.

Taken together, this suggests that both the receptors themselves, and the patterns of neuron activity are necessary for psilocybin to really work.

THE FUTURE OF MAGIC MUSHROOMS

Knowing that both receptors and neuron activity are needed, says Kringlebach, could help better understand how to use the drug as a therapy. In turn, these models can help us visualize an enduring mystery within the human brain, says Kringlebach.

“It has long been a puzzle how the brain’s fixed anatomical connectome can give rise to so many radically different brain states; from normal wakefulness to deep sleep and altered psychedelic states,” he says.

We only have a fixed amount of hardware in the brain, yet we’re running highly complicated software that produces dreams, consciousness, and — if someone is on a drug like DMT — “breakthrough experiences.”

If the magic mushrooms demonstrate anything, it’s that the brain can learn to use its fixed hardware in very different ways, if the right ingredients are involved. The trick is figuring out what tools the brain needs to run different types of software on that hardware.

In the future, the team hopes that their model could help us learn how we can run different types of software in our brains, and in doing so, help treat conditions like depression.

“This new model will give us the much needed, causal tools for potentially designing new interventions to alleviate human suffering in neuropsychiatric disorders,” Kringlebach says.

Recent therapeutic trials of “classical” psychedelic drugs, such as psilocybin (from magic mushrooms) or LSD, have reported benefits to wellbeing, depression and anxiety. These effects seem to be linked to a sense of “ego dissolution” — a dissolving of the subjective boundaries between the self and the wider world. However, the neurochemistry behind this effect has been unclear. Now a new paper, published in Neuropsychopharmacology, suggests that changes in brain levels of the neurotransmitter glutamate are key to understanding reports of ego dissolution — and perhaps the therapeutic effects of psychedelics.

Natasha Mason at Maastricht University, the Netherlands, and colleagues recruited 60 participants for their study. All had taken a psychedelic drug before, but not in the three months prior to the study. Half received a placebo and the other half were given a low to moderate dose of psilocybin (0.17 mg/kg of body weight).

The team then used a technique called proton magnetic resonance spectroscopy (MRS) to look at concentrations of glutamate (as well as other neurochemicals) in the medial prefrontal cortex (mPFC) and the hippocampus — two regions that have been implicated as key to the psychedelic drug experience. The team also looked at patterns of “functional connectivity” within networks of brain regions, a measure of how closely correlated brain activity is across those regions. Six hours after taking the drug or placebo, the participants reported on their subjective experiences using two surveys: The 5 Dimensions of Altered States of Consciousness and the Ego Dissolution Inventory.

As the researchers expected (based on the findings of earlier research), those given the drug reported increased feelings of ego dissolution, as well as altered states of consciousness. They also showed disruptions in the connectivity of particular networks, including the default mode network, which has also been implicated in past work on the effects of psychedelic drugs..

But, for the first time in humans, the team also observed higher levels of glutamate in the mPFC and lower levels in the hippocampus after taking psilocybin — and they linked these changes to different aspects of ego dissolution. Increases in the mPFC were most strongly linked to unpleasant aspects, such as a loss of control over thoughts and decision-making, and also anxiety. Decreases in the hippocampus, meanwhile, were most strongly linked to more positive aspects, such as feelings of unity with the wider world, and of having undergone a spiritual-type experience.

The hippocampus is our most important memory structure. Based on earlier work on the impacts of psychedelic drugs on patterns of brain connectivity, it’s been suggested that a temporary reduction or loss of access to memories about our own lives might contribute to a weakening of the “self”. The new work suggests that changes in glutamate levels in the hippocampus might be key to this process.

But if glutamate rises in the mPFC are linked to unpleasant aspects of ego dissolution, and also to anxiety, how does this fit in with trial results finding that psychedelic drugs can treat anxiety disorders?

It’s not entirely clear. Psychedelics are known to bind with one particular type of serotonin receptor, called 5-HT2A receptors. This then causes immediate changes in the glutamate system, which could be responsible for producing short-term feelings of anxiety. But it might be that longer-term reduction in anxiety levels is related more to 5-HT2A receptor activation itself, rather than glutamate, the researchers suggest.

It’s also been suggested that activation of glutamate networks (via the 5-HT2A receptor) increases levels of Brain-Derived Neurotrophic Factor, which promotes the health and growth of new brain cells. Animal work provides evidence that psychedelic drugs indeed promote plasticity in the brain. And people with major depression and stress disorders have been found to have reduced plasticity. The new data provide indirect evidence that psychedelics might increase neuroplasticity in the human cortex by increasing glutamate, the researchers write. If correct, this could help with understanding how psychedelic drugs can treat depression.

More work is clearly needed to fully understand all these processes. But there’s a lot of interest in the potential therapeutic benefits of psychedelic drugs right now, and the new study does help to clarify the underlying neurobiology of the psychedelic state. As the researchers write, the findings “provide a neurochemical basis for how these substances affect individuals’ sense of self, and may be giving rise to therapeutic effects witnessed in ongoing clinical trials.”

How Long Do Shrooms Last?

How do shrooms work?

how long do shrooms last?

Psilocybin mushrooms, commonly known as magic mushrooms, or more simply, shrooms, are considered a psychedelic. Psychedelics are commonly known as drugs with hallucinogenic effects, and while that is partially true, psychedelics are actually a very specific set of drugs that can bond to the 5-HT2a serotonin receptor.

Shrooms contain a drug called psilocybin. When ingested, your body breaks that psilocybin down into its dephosphorylated cousin, psilocin. Psilocin is molecularly very close to serotonin – a naturally-occurring neurotransmitter in humans, other mammals, and even some worms and insects as well as plants and fungi. It’s so close to serotonin, in fact, that it’s capable of bonding with certain serotonin receptors, especially the 5-HT2a receptor. It’s not perfectly understood how exactly shrooms cause their psychedelic trips, it’s understood that it has to do with this interaction.

How long do shrooms take to kick in?

How long it will take for you to start feeling the effects of magic mushrooms depends primarily on how they are ingested. If the mushrooms are eaten as whole mushrooms, the onset can be anywhere from 20-40 minutes. If the mushrooms are ground into a fine powder and mixed with lemon juice or made into tea, the onset can be much faster – around 5-10 minutes. Gummies and chocolates tend to come on in about 15-30 minutes.

How long does a shroom trip last?

How long your magic mushroom trip is going to last will depend primarily on the following factors:

 

  • How much did you take?
    You should be able to quantify this in the weight of the dried product for consistent measuring.
  • What kind of shroom did you take?
    You can read details about all the different kinds of shrooms in our shroom shop – but some tend to last longer than others.
  • How were they taken?
    As a general rule of thumb, whole shrooms will last a little longer but produce a more mellow trip, and teas/chocolates/gummies tend to be more intense, but shorter in duration.
  • Who’s taking them?
    A number of factors matter here: height, weight, age and all play a role. People who have consumed psilocybin recently will also exhibit higher tolerance to subsequent doses. There are also certain pre-existing medical conditions that can affect the overall duration of the trip.
  • Have you taken any other drugs?
    It can be hard enough to estimate what psilocybin will do and how it will last; adding other psychoactive drugs can have unpredictable effects on the overall experience.
  • Are you in a calm and peaceful, or a more high-energy environment?
    The kind of energy that you surround yourself with and take in while you’re tripping will affect a number of things, including the duration of the trip.


And many more. In general, you should budget about 4-8 hours for the trip to completely end, including any sort of “afterglow.” Typically the peak will be around 1-2 hours in, and will fade from there – although it is common to experience “waves,” so if you think you feel yourself coming down, don’t be caught off guard if it was just a bump on the roller coaster!

What’s it like coming down from shrooms?

coming down from shrooms

Coming down from shrooms by most accounts is considered to be a generally pleasant experience as compared with coming down off other drugs. Psilocybin is not inherently addictive, and it is quite rare for people to get addicted to mushrooms. There are a few reasons for this – but a big one is thought to be the fact that psilocybin doesn’t affect the body’s dopamine receptors. Most addictive substances somehow manipulate the body’s regulation of dopamine. Dopamine is the chemical that makes us feel motivated, accomplished, and productive while serotonin (which is what psilocin mimics) is what makes us feel calm, relaxed, and happy.

In general, your “come down” from shrooms will be about the back half of your trip. So, a 6-hour trip you might spend 1 hour climbing, 2 hours speaking, and 3 hours “coming down.” It’s a very gentle kind of experience that tends to lend itself well to introspection and deep conversations. It’s a really important and wonderful part of the experience, because it gives you time to connect the wild thoughts and deep insights that came to you from the fungus with your conscious, sober mind.

This is also a great time to journal about your experience, and record your thoughts. Just make sure not to jump behind the wheel of a car or anything, until you’re sure you’re firmly planted back in reality.

How Long Do shrooms stay in your system?

Shrooms are almost completely flushed from the body’s system within 24 hours. If you’re being tested for drugs, shrooms are completely undetectable after 48 hours in urine tests. Traces can last up to 90 days in hair follicles, but this form of testing is extremely unlikely.

Unlike with LSD which can have a longer half-life, psilocybin and psilocin are both completely broken down by the body and expelled within a couple days. The chances of experiencing flashbacks, etc. as you might have heard of before is also quite small.

How long are shrooms detectable in a drug test?

how long are shrooms detectable in a drug test

Shrooms are detectable in your urine up to 48 hours after consumption – so if you’re planning a camping trip with some buddies, try not to have to piss in a cup on Monday morning. It is, however, quite likely that shrooms will go completely undetected, as the majority of commonly used urine tests for drug use do not actually search for psilocybin or psilocin.

It’s worth mentioning that there are certain drug tests that are capable of detecting much more trace amounts of psilocybin in the body’s hair follicles, and those can stick around for 90 days. These are extremely uncommon in day-to-day use though – so if you’re not training for a boxing match, or applying to the CIA, you should be A-OK.

Summary

So, there are a number of factors but the Cole’s Notes:

Shrooms will last in total anywhere from 4-8 hours.

You’ll be at the “peak” of your high from about a quarter of the way through to halfway through, and start coming down from there.

Shrooms will be completely undetectable in a urine test after 48 hours, and all traces will be gone from your body within 90 days.

Why do Magic Mushrooms Cause Nausea?

Introduction


So, if you’ve ever done magic mushrooms, it’s extremely likely that you’ve experienced the nausea that is widely reported as one of the most common unpleasant side effects of ingesting psilocybin mushrooms. Often, this is a mild nausea that starts to come on about 15-20 minutes after ingesting the mushrooms, before the psychoactive effects kick in – but sometimes, it resurfaces later in the experience. For most, it’s a nuisance that passes relatively quickly, but sometimes can be quite severe and even result in vomiting. So, what is it exactly that causes nausea? Why does it happen? And maybe most importantly, what (if anything) can we do about it? All this and more, answered in this article!

How Humans Digest Mushrooms
How Humans Digest Mushrooms

Obviously, magic mushrooms are different than their non-psychoactive counterparts, but mycologically speaking, aside from the presence of the psychoactive compounds psilocybin and psilocin, the human body digest magic mushrooms in much the same way as it digests normal mushrooms – so looking at what we know about how mushrooms are digested might offer the first clues. Paul Stamets is the author of Psilocybin Mushrooms in the World, a leading mycologist, and psychonaut who has been at the forefront of helping to classify and organize human knowledge around magic mushrooms for some time. He explained that, outside of instances where people are looking to eat mushrooms for their psychoactive potential, we should almost never be eating mushrooms raw.


“Raw mushrooms are largely indigestible because of their tough cell walls, mainly composed of chitin. Raw mushrooms and raw mycelium may pose health hazards from harmful pathogens and heat-sensitive toxins—potentially causing red blood cell damage, gastrointestinal irritation, and allergic reactions, such as skin rashes.” – Dr. Paul Samets

Another mushroom expert, Dr. Andrew Weil, in an article on his website, noted that “mushrooms have very tough cell walls and are essentially indigestible if you don’t cook them. Thoroughly heating them releases the nutrients they contain, including protein, B vitamins, and minerals, as well as a wide range of novel compounds not found in other foods.” He goes on to explain that not only is the chitin material that composes the cell walls indigestible, but it’s possible for it to cause inflammatory and immune responses in the process of being broken down. Chitin doesn’t occur naturally in the human body, but we do produce an enzyme called chitinase – this enzyme breaks up the chitin in our system, and the smaller molecules that occur as a result of this breaking down can potentially cause these inflammatory responses. So, when it comes to mushrooms that are being used for culinary purposes, on all fronts it seems like the best bet is to simply prepare them beforehand by cooking them in any number of different ways. However, cooking shrooms is not necessarily the best option when we’re talking about magic mushrooms. This is because heating them can destroy the psychedelic compounds; this is why magic mushrooms are traditionally eaten raw, or, most commonly, dried. It’s entirely possible that the nausea experienced from eating magic mushrooms is simply related to eating raw chitin, but there are some other ideas that have surfaced related to the different array of chemicals that can be found in magic mushrooms.

The Other Chemicals in Magic Mushrooms

So, it’s well-known (and we’ve even mentioned earlier in this article) that psilocybin and pislocin are the two main compounds found in magic mushrooms that give them their psychedelic properties. There are a number of these compounds, but the most prevalent are baeocystin, norbaocystin, norpsilocin, aeruginascin and phenethylamine. Each of these compounds are similar to psilocybin, varying primarily in the different methyl groups on their amines. We do have records of studies in which people have taken pure, synthetic psilocybin and reported nausea as a side effect. These people had never taken mushrooms before and were not told beforehand to expect nausea as a side-effect, so it’s highly unlikely that this was a placebo effect.

So, contrasting what we just read in the preceding section, there may be something specific about the psilocybin compound itself that causes nausea, even when isolated from the other compounds found in the mushroom. We also know that the human body process psilocybin into psilocin in the process of digestion, and so it might be the psilocin being formed, or a side-effect of the processing that causes these issues Of all the compounds we listed, phenylethylamine is the most distinct.

Phenethylamine is a central nervous system stimulant and neurotransmitter that has potential hallucinogenic effects in humans. Amphetamine, methamphetamine, and MDMA are all examples of phenethylamines that enjoy widespread use in modern society for recreational, medicinal, and therapeutic effects. It’s also widely noted that these substances can cause side effects such as raising heart rate, increasing blood pressure, and inducing – you guess it – nausea. However, Alexander Shulgin (author of the famous books, Phenethylamines I Have Known and Loved and Tryptamines I Have Known and Loved,) believes it is unlikely that phenethylamines in mushrooms are responsible for these effects. According the Shulgin, phenethylamines by themselves are “rapidly and completely destroyed” when ingested by humans, and that it’s only in the presence of a specific set of other molecules that phenethylamines will remain intact long enough for their psychopharmacological effects to be felt – and that these molecules are not present in psilocybin mushrooms.

The Role of Beta-Glucan

So, we’ve isolated the potentially nauseating components of magic mushrooms to: the chitin in the cell walls, and the psilocybin itself. Obviously, we don’t want want to do anything that would eliminate psilocybin from the mushrooms, as that would defeat the entire purpose – but can something be done about the chitin? Well, in order to understand that, we first need to understand what’s actually happening when it’s being broken down in the stomach. Biologist Ian Bollinger says that even though no one has pinned down exactly what it is that’s causing the nausea, there’s strong evidence that points to a substance called beta-glucan. Beta-glucan is a type of sugar that’s commonly found in oats, and other grains, but is found in significantly more abundance in the chitin of the mushroom cell walls.

His theory is that the excess amount of beta-glucan as it’s broken down in the stomach causes a reaction, because the stomach is acidic, and beta-glucan is basic – if you remember your elementary school science class lessons of missing vinegar and baking soda, that should be a quick reminder of what can happen when acids and bases are mixed! There’s more evidence to support this theory as well. Beta-glucan is sometimes taken as a supplement for people with high cholesterol, or who suffer from other heart health problems. One of the noted side effects of taking beta-glucan supplements is, you guessed it, nausea. Therefore, it seems likely that the nausea caused by ingesting magic mushrooms is largely attributable to the chitin in the cell walls, and the psilocybin compound itself. It’s also worth noting that the symptoms of nausea are far more likely to be experienced if a person is already dehydrated or in poor physical health, and also when taking exceedingly large doses. All of this is great, but… nausea still sucks! And is there anything we can do about it? Well, fear not fellow psychonaut – we have some answers that should help you with that, too!

How to Reduce Nausea When Taking Magic Mushrooms

Magic Mushrooms Citrus Bath
A Citrus Bath with Lemon Juice Will Help With Nause from Magic Mushrooms

So, if the prospect of experiencing nausea or potentially vomiting is enough to dissuade you from taking mushrooms, even though you think the experience might otherwise be beneficial for you, then there is something you can do that has been shown to help reduce the experience of nausea, if not eliminate it altogether. So, what is this “One Simple Trick to Make Mushrooms Go Down Easier?” (Damn – I probably should have named the article that!) Well, it’s pretty simple – and it comes back down to the relationship between the stomach acid and beta-glucan. And the trick is, essentially, using lemon juice. It looks like this:

1: Grind the mushrooms into a fine powder, or as small pieces as possible.

2: Put the powder in a glass

3: Pour enough lemon juice to submerge the powder completely, and stir for 1 minute.

4: Down the hatch!


The reason that this works, according to Bollinger, is that the lemon juice has around the same Ph level as your stomach acid. By exposing the cell walls of the mushroom and the beta-glucan to lemon juice, it begins the process of breaking it down before the mushrooms are ingested, resulting in less of a reaction once the mushrooms reach the stomach acid. This technique has been used by many people who have reported favourable results, although there are certainly some caveats that should be considered.

The first thing that should be considered is that a citrus bath will actually cause the onset of your trip to come on faster, be greater in intensity, and last for a shorter period of time. In Bollinger’s own words, “Lemon juice is an aqueous solution with a low Ph,” Bollinger explains. “Low Ph means excessive hydrogens. Putting psilocybin in that solution removes the phosphate group and replaces it with a hydroxyl group. That turns it into psilocin. If you think of the experience like a bell curve,” Bollinger says, “with the effects slowly ramping up, peaking, and ramping back down, a lemon [bath] will compress it. What you’re doing is heightening the curve but you’re also shortening the length.” Depending on the kind of experience you’re looking for, a shorter, more intense high might suit your needs – but it’s good to understand that the citrus bath will affect how the high actually happens. Secondly, it’s important to understand that although the citrus bath will help mitigate the experience of nausea caused by ingesting magic mushrooms, it won’t necessarily get rid of it altogether. As mentioned before, it seems like the human body has a tendency to react to psilocybin by itself with a slight nausea, so even if you are treating your mushrooms with a citrus bath, you should still be expecting the nausea.

An even easier solution would be to take a look at our selection of magic mushroom teas.

Advice from Reddit

If that’s not enough for you guys, I’ve consolidated some of the advice users have provided on the forum Reddit, here: One user recommends a more refined citrus bath:

1 – go to the store, buy a lemon or lime, whichever you prefer the taste of.

2 – grind up your shrooms with either a grinder or your fingers. Both work just fine.

3 – put the shrooms in a french press and squeeze the lemon or lime into the french press until the little bits are fully covered.

4 – Stirring every so often, let the sludge sit for about 30 minutes. To better understand what is going on here, just look up lemon-tek.

5 – Put some ginger, your favorite tea (I prefer chamomile for this), some honey (or sugar if you have no honey) into the mix.

6 – bring water to an almost boil and then pour it into the french press.

7 – put the lid and such on and put the french press aside. Go take a shower and get ready for your trip.

8 – once you are done showering, give it a good stir and press the french press filter down as far as it will go.

9 – pour yourself a nice warm cup of tea and enjoy it; make sure you get ALL the liquid out. Some suggest squeezing the bits until they are dry and others don’t care. This is up to you. I prefer to not gulp it all down as I love the taste and love tea. some friends however prefer to just pound it. whatever’s clever for you.

This will do a few things. First, the lemon tek will help offload some of the psilocybin->psilocin process from your stomach. While this will not do much for nausea, it will kick-start the trip sooner and can yank you right past the anxiety and anticipation stage if that also bugs you. Second, part of what makes most nauseous comes from when the body tries to break down the cellular wall on the shrooms. By not putting this in your system, you are going to find that you won’t feel nauseous at all, or shouldn’t.

When eating them, I used to feel so damn sick through an entire trip that it would ruin my trips. By making tea, I am able to enjoy all that the shrooms have to offer without a worry of nausea.

I hope this helps!

MUSH LOVE!

Closing Thoughts

In summary, there are a few different methods you can try – but by all accounts, the most consistent and best method seems to be the preemptive citrus bath. In addition, some quick tips that will help to mitigate the nausea: – Eat a light snack beforehand. Not a full meal, which might delay the onset and offset the potency of the high, but enough that the shrooms aren’t going down on a completely empty stomach. – Make sure you’re well-rested and hydrated. Lack of sleep and dehydration can cause nausea by themselves, no reason to add tinder to the fire. – Don’t mix mushrooms with other drugs. This is just generally good advice – but the more psychoactive chemicals you’re mixing together, the more likely your body is to have an adverse reaction. Play it on the safe side, and keep them separate!

Long Term Effects of Magic Mushrooms – Everything you Need to Know 2021

Long Term Effects of Magic Mushrooms

Magic mushrooms are the safest of all recreational drugs

For most of us who grew up and went to school in Canada — and probably everywhere else, for that matter — warnings about the harms of “drugs” were so pervasive that just reading the title of this article, Long Term Effects of Magic Mushrooms, probably conjures up a bit of fear. Surely these “long term effects” will be bad!

But what does the most up to date research actually tell us about the effects of psilocybin (the active ingredient in magic mushrooms)? Were these well intended warnings we got from our teachers and parents actually based in reality? And is it possible that the long term effects of magic mushrooms might actually be positive?

In this article we aim to paint a more realistic picture of the risks and benefits of magic mushrooms, and to show that the fears we might be carrying about their long term effects are likely unwarranted.

Magic Mushrooms In History

Long Term Effects of Magic Mushrooms

Varieties of magic mushrooms are found growing on every continent on earth (except, obviously, Antarctica), and there is evidence for their use by humans going back thousands of years, in places as widely separated as Mesoamerica, Australia, and ancient Greece.

None of this ancient world use of magic mushrooms automatically rules out the possibility of negative long term effects — it’s probably tricky to detect long term effects when hardly anybody’s living past age 50 — but at the very least the consistent use for thousands of years by cultures around the globe suggests that nobody noticed anything going wrong. It’s a starting point.

And it’s not all ancient history: shamans and healers in the Mesoamerican region use psychedelics in ritual ceremonies to this day, and don’t seem worried about it.

But us supposedly scientific minded folk, we like our studies. So what, if anything, do our studies say?

Short Term vs Long Term

Let’s start with the short term.

By short term we mean the trip itself, or the same day. We have a pretty good idea about the obvious and easy to describe short term effects like euphoria, vivid colours and other visual effects, as well as the potential short term dangers (which are rare, usually related to anxiety or panic, and “successfully managed by providing interpersonal support”).

Less obvious positive short term effects might include a boost to creativity and empathy or even increased neuroplasticity through neuritogenesis.

Long term is harder to define. A recent (2020) study that showed psilocybin’s supposed “long term” positive effect on mood showed that lasting effect by following up a mere one month later! But while that’s interesting, we’re probably less concerned with what happens a month later. We want to know if magic mushrooms will do something to us that only shows up way down the road — perhaps along the lines of radiation damage from too much sun, or heart disease from lack of exercise.

The trouble is that magic mushrooms only entered the awareness of US and Canadian culture in 1957, with the first documented recreational use of magic mushrooms in Vancouver in 1965. That, along with magic mushrooms being mostly illegal since the seventies, has put a limit on how much long term research there can be.

But there is some longer term research.

The Surprising (?) Results of Longer Term Studies

Long Term Effects of Magic Mushrooms

Anyone searching for studies showing negative long term effects from using magic mushrooms quickly runs into a problem: there aren’t any.

In his book “Drugs Without the Hot Air: Making Sense of Legal and Illegal Drugs” (2020), author David Nutt assesses psilocybin to be the least harmful drug, ten times less harmful than the worst drug (alcohol). In their paper, “Psychedelics and Mental Health: A Population Study”, authors Teri S. Krebs and Pål-Ørjan Johansen open with the following claims.

“The classical serotonergic psychedelics LSD, psilocybin, mescaline are not known to cause brain damage and are regarded as non-addictive. Clinical studies do not suggest that psychedelics cause long-term mental health problems. Psychedelics have been used in the Americas for thousands of years. Over 30 million people currently living in the US have used LSD, psilocybin, or mescaline.”

Yes, there are cases of negative effects to be found here and there, but it’s very difficult to find widespread long term negative effects that hold up to scrutiny. The biggest example, the one that comes up the most often, is the idea of “flashbacks”, or, “hallucinogen persisting perceptual disorder” (HPPD). Krebs and Johansen discuss this issue, and though they are here referencing LSD and peyote as well as psilocybin, it’s worth hearing what they have to say.

“In this study, lifetime use of psychedelics and past year use of LSD was not associated with past year symptoms of visual phenomena (‘‘seeing something others could not’’), panic attacks, psychosis, or overall serious psychological distress. Thus, our findings does not support either the idea of ‘‘flashbacks’’ described in extreme cases as recurrent psychotic episodes, hallucinations, or panic attacks, or the more recent ‘‘hallucinogen persisting perceptual disorder’’ (HPPD) described as persistent visual phenomena with accompanying anxiety and distress…. Overall, the validity of the HPPD diagnosis remains scant.”

Evidence of long term harm may yet be discovered, but at this point it’s almost impossible to find any.

There are, however, some interesting positive results.

Long-Term Benefits of Magic Mushroom Use

Long Term Effects of Magic Mushrooms

For example, a study that suggests that psilocybin can have an effect on the personality trait of openness, one of the “five broad domains of personality”, and that the effect of increased openness was stable a full year later.

There is a less robust but still interesting paper that suggests that psilocybin assisted therapy can have a positive effect on the mental health of cancer patients four years later.

Or a 2013 paper where, “21,967 respondents (13.4% weighted) reported lifetime psychedelic use. There were no significant associations between lifetime use of any psychedelics, lifetime use of specific psychedelics (LSD, psilocybin, mescaline, peyote), or past year use of LSD and increased rate of any of the mental health outcomes. Rather, in several cases psychedelic use was associated with lower rate of mental health problems.”

Yes, the group that had used psychedelics at some point in their life in several cases had a lower rate of mental health problems.

There’s even a survey showing some success with using psilocybin to quit smoking, with the results lasting over two years.

Positive results are very easy to find — and more are coming all the time.

What are the Long Term Effects of Magic Mushrooms?

All that said, it’s difficult to give a truly conclusive answer about the long term effects of magic mushrooms. While there are positive studies, a long history of use all around the world, and no research showing evidence of long term harm, nobody has yet done the large scale, long term, high quality studies that would be needed to remove all doubt.

The government of Canada’s website offers that, “Currently, no studies have evaluated the long-term effects of repetitive use of magic mushrooms.” And that’s not completely unfair. Much of the work cited above regarding long term effects is using the best available data, but that data is sometimes old, or self reported and based on surveys. Solid as far as it goes, but not as conclusive as one might hope.

We expect that as the world reopens to the possibilities of magic mushrooms — see for example Oregon’s successful 2020 vote to legalize psilocybin — research will get easier, and we might begin to get the full and definitive picture of their long term effects.

In the meantime, we can say this: the best evidence available today suggests a range of possibilities. At worst there may be no detectable long term effects from magic mushrooms at all. And at best there may be positive ones.

The image from the very top of this post, which we will also leave directly below for convenience is taken from TripSafe – a website for education on psychedelics like shrooms and LSD. It shows that in comparison with virtually every other “drug” known to mankind, mushrooms are the safest and least addictive. We don’t know everything about the long term effects of psychedelic mushroom use, but there is one fact that seems abundantly clear and is supported by virtually all of the research into the subject:

Magic mushrooms remain the safest of all recreational drugs.

Long Term Effects of Magic Mushrooms

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